1JPI

Phe232Leu mutant of human UROD, human uroporphyrinogen III decarboxylase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	UROPORPHYRINOGEN DECARBOXYLASE	polymer	388	43331.5	1	UniProt (P06132) Pfam (PF01208) In PDB	Homo sapiens (human)	UroD, UPD, uro'gen III decarboxylase
2		water	water		18.0	287	Chemie (HOH)

Sequence modifications

A: 1 - 367 (UniProt: P06132)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
His -5	-	expression tag
Ile -4	-	expression tag
Glu -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
His 0	-	expression tag
Leu 232	Phe 232	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43331.5
All*	Total formula weight	43331.5

*Water molecules are not included.