1JMU

Crystal Structure of the Reovirus mu1/sigma3 Complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	PROTEIN MU-1	polymer	41	4050.4	3	UniProt (P11077)	Reovirus sp.
2	B, D, F (B, D, F)	PROTEIN MU-1	polymer	666	72182.7	3	UniProt (P11077) Pfam (PF05993)	Reovirus sp.
3	G, H, I (G, H, I)	SIGMA 3 PROTEIN	polymer	366	41263.2	3	UniProt (Q86292) Pfam (PF00979) UniProt (by SIFTS) (P07939)	Reovirus sp.	MAJOR OUTER CAPSID PROTEIN
4	J (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	K, M, O (B, D, F)	octyl beta-D-glucopyranoside	non-polymer		292.4	3	Chemie (BOG)
6	L, N, P, R, S... (B, D, F, G, H...)	SULFATE ION	non-polymer		96.1	9	Chemie (SO4)
7	Q, T, W (G, H, I)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
8	AA, BA, CA, DA, EA... (B, C, D, E, F...)	water	water		18.0	271	Chemie (HOH)

Sequence modifications

B, D, F: 43 - 708 (UniProt: P11077)

PDB	External Database	Details
Pro 272	Leu 272	SEE REMARK 999
Lys 284	Arg 284	SEE REMARK 999
Leu 344	Pro 344	SEE REMARK 999
Phe 359	Leu 359	SEE REMARK 999

G, H, I: 1 - 365 (UniProt: Q86292)

PDB	External Database	Details
Cys 104	Ala 104	engineered mutation
Asn 325	Asp 325	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	352488.9
Non-Polymers*	Number of molecules	16
	Total formula weight	1973.4
All*	Total formula weight	354462.3

*Water molecules are not included.