1JD0
CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CARBONIC ANHYDRASE XII COMPLEXED WITH ACETAZOLAMIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CARBONIC ANHYDRASE XII | polymer | 263 | 29857.2 | 2 | UniProt (O43570) Pfam (PF00194) | Homo sapiens (human) | CARBONATE DEHYDRATASE XII, CA-XII, TUMOR ANTIGEN HOM-RCC-3.1.3 |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE | non-polymer | 222.2 | 2 | Chemie (AZM) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 504 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 262 (UniProt: O43570)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Gly 30 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59714.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 575.3 | |
| All* | Total formula weight | 60289.7 |
