1J7Y
Crystal structure of partially ligated mutant of HbA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Hemoglobin | polymer | 141 | 15222.4 | 2 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (human) | |
| 2 | B, D (B, D) | Hemoglobin | polymer | 146 | 15962.3 | 2 | UniProt (P68871) Pfam (PF00042) | Homo sapiens (human) | |
| 3 | E, H, J, K (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 4 | F, G (B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | I, L (B, D) | CARBON MONOXIDE | non-polymer | 28.0 | 2 | Chemie (CMO) | |||
| 6 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 440 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 141 (UniProt: P69905)
B, D: 1 - 146 (UniProt: P68871)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | Val 1 | engineered mutation |
| Tyr 29 | Leu 29 | engineered mutation |
| Gln 58 | His 58 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | Val 1 | engineered mutation |
| Tyr 28 | Leu 28 | engineered mutation |
| Gln 63 | His 63 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62369.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2714.1 | |
| All* | Total formula weight | 65083.5 |
