1J7W

Crystal structure of deoxy HbbetaYQ, a site directed mutant of HbA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	hemoglobin	polymer	141	15182.4	2	UniProt (P69905) Pfam (PF00042)	Homo sapiens (human)
2	B, D (B, D)	hemoglobin	polymer	146	15962.3	2	UniProt (P68871) Pfam (PF00042)	Homo sapiens (human)
3	E, F, G, H (A, B, C, D)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	4	Chemie (HEM)
4	I, J, K, L (A, B, C, D)	water	water		18.0	246	Chemie (HOH)

Sequence modifications

A, C: 1 - 141 (UniProt: P69905)

PDB	External Database	Details
Met 1	Val 1	engineered mutation

B, D: 1 - 146 (UniProt: P68871)

PDB	External Database	Details
Met 1	Val 1	engineered mutation
Tyr 28	Leu 28	engineered mutation
Gln 63	His 63	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	62289.4
Non-Polymers*	Number of molecules	4
	Total formula weight	2465.9
All*	Total formula weight	64755.3

*Water molecules are not included.