1J4A

INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	D-LACTATE DEHYDROGENASE	polymer	333	37112.2	4	UniProt (P26297) Pfam (PF00389) Pfam (PF02826)	Lactobacillus delbrueckii subsp. bulgaricus	D-LDH
2	E, F, G, H, I... (A, B, C, D)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
3	P, Q, R, S (A, B, C, D)	water	water		18.0	900	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 333 (UniProt: P26297)

PDB	External Database	Details
Ile 59	Thr 59	SEE REMARK 999
Arg 117	Ala 117	SEE REMARK 999
Val 152	Ile 152	SEE REMARK 999
Lys 297	His 297	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	148448.6
Non-Polymers*	Number of molecules	11
	Total formula weight	1056.7
All*	Total formula weight	149505.3

*Water molecules are not included.