1J17
FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH RAT TRYPSIN MUTANT X99/175/190RT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | T | Trypsin II, anionic | polymer | 223 | 23836.8 | 1 | UniProt (P00763) Pfam (PF00089) In PDB | Rattus norvegicus (Norway rat) | TRYPSINOGEN, BETA-TRYPSIN, Pretrypsinogen II |
| 2 | T | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | T | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | T | [4-(6-CHLORO-NAPHTHALENE-2-SULFONYL)-PIPERAZIN-1-YL]- (3,4,5,6-TETRAHYDRO-2H-[1,4']BIPYRIDINYL-4-YL)- METHANONE | non-polymer | 499.0 | 1 | Chemie (ZEN) | |||
| 5 | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence modifications
T: 16 - 245 (UniProt: P00763)
| PDB | External Database | Details |
|---|---|---|
| Glu 97 | Lys 102 | engineered mutation |
| Tyr 99 | Leu 104 | engineered mutation |
| Ser 172 | Tyr 175 | engineered mutation |
| Ser 173 | Pro 176 | engineered mutation |
| Phe 174 | Gly 177 | engineered mutation |
| Ile 175 | Lys 178 | engineered mutation |
| Ala 190 | Ser 195 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23836.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 635.2 | |
| All* | Total formula weight | 24471.9 |
