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1IW7

Crystal structure of the RNA polymerase holoenzyme from Thermus thermophilus at 2.6A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, G, H
(A, B, K, L)
RNA polymerase alpha subunitpolymer31535056.24UniProt (Q9Z9H6)
Pfam (PF01193)
Pfam (PF01000)
Pfam (PF03118)
Thermus thermophilus
2C, I
(C, M)
RNA polymerase beta subunitpolymer1119125436.52Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF10385)
Pfam (PF00562)
Pfam (PF04560)
UniProt (by SIFTS) (Q8RQE9)
Thermus thermophilus
3D, J
(D, N)
RNA polymerase beta subunitpolymer1524170997.42Pfam (PF04997)
Pfam (PF21668)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
UniProt (by SIFTS) (Q8RQE8)
Thermus thermophilus
4E, K
(E, O)
RNA polymerase omega subunitpolymer9911521.22Pfam (PF01192)
UniProt (by SIFTS) (Q8RQE7)
Thermus thermophilus
5F, L
(F, P)
RNA polymerase sigma-70 subunitpolymer42348568.02GenBank (4239959)
Pfam (PF00140)
Pfam (PF04542)
Pfam (PF04539)
Pfam (PF04545)
UniProt (by SIFTS) (Q72L95)
Thermus thermophilus
6AA, AB, AC, AD, AE...
(A, B, C, D, F...)
MAGNESIUM IONnon-polymer24.3485Chemie (MG)
7ND, NN, OD, ON
(D, N)
LEAD (II) IONnon-polymer207.24Chemie (PB)
8HS, IS, JS, KS, LS...
(A, B, C, D, E...)
waterwater18.05476Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight853271.0
Non-Polymers*Number of molecules489
Total formula weight12616.7
All*Total formula weight865887.7
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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