1IVC
STRUCTURES OF AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | INFLUENZA A SUBTYPE N2 NEURAMINIDASE | polymer | 388 | 43141.0 | 2 | UniProt (P06820) Pfam (PF00064) | Influenza A virus (strain A/Tokyo/3/1967 H2N2) | |
| 2 | C, F, G, J (C, F, G, J) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D (D) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G86566TX) | |||
| 4 | E, I (E, I) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 2 | In PDB GlyTouCan (G19158MO) | |||
| 5 | H (H) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 6 | K, M (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 7 | L, N (A, B) | 4-(ACETYLAMINO)-5-AMINO-3-HYDROXYBENZOIC ACID | non-polymer | 210.2 | 2 | Chemie (ST2) |
Sequence modifications
A, B: 82 - 469 (UniProt: P06820)
| PDB | External Database | Details |
|---|---|---|
| Asp 339 | Asn 339 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86282.0 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 5308.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 500.5 | |
| All* | Total formula weight | 92091.4 |
