1ISI
Crystal Structure Analysis of BST-1/CD157 complexed with ethenoNAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | bone marrow stromal cell antigen 1 | polymer | 265 | 30172.2 | 2 | UniProt (Q10588) Pfam (PF02267) | Homo sapiens (human) | BST-1/CD157, ADP-ribosyl cyclase 2 |
| 2 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E, G (A, B) | NICOTINAMIDE | non-polymer | 122.1 | 2 | Chemie (NCA) | |||
| 4 | F, H (A, B) | [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-imidazo[2,1-f]purin-6-ium-3-yl)oxolan-2-yl]methoxy-oxidanidyl-phosphoryl] [(2R,3S,4R,5R)-3,4-dihydroxy-5-oxidanidyl-oxolan-2-yl]methyl phosphate | non-polymer | 582.3 | 2 | Chemie (ENQ) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 265 (UniProt: Q10588)
| PDB | External Database | Details |
|---|---|---|
| Asp 34 | Asn 66 | engineered mutation |
| Thr 63 | Asn 95 | engineered mutation |
| Ala 116 | Asn 148 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60344.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1408.9 | |
| All* | Total formula weight | 62602.1 |
