1IOG

INSULIN MUTANT A3 GLY,(B1, B10, B16, B27)GLU, DES-B30, NMR, 19 STRUCTURES

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PROTEIN (INSULIN PRECURSOR)	polymer	21	2341.6	1	UniProt (P01308)	Homo sapiens (human)
2	B (B)	PROTEIN (INSULIN PRECURSOR)	polymer	29	3299.7	1	UniProt (P01308) Pfam (PF00049)	Homo sapiens (human)

Sequence modifications

A: 1 - 21 (UniProt: P01308)

PDB	External Database	Details
Gly 3	Val 92	engineered mutation

B: 1 - 29 (UniProt: P01308)

PDB	External Database	Details
Glu 1	Phe 25	engineered mutation
Glu 10	His 34	engineered mutation
Glu 16	Tyr 40	engineered mutation
Glu 27	Thr 51	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	5641.3
All*	Total formula weight	5641.3

*Water molecules are not included.