1IND
HOW THE ANTI-(METAL CHELATE) ANTIBODY CHA255 IS SPECIFIC FOR THE METAL ION OF ITS ANTIGEN: X-RAY STRUCTURES FOR TWO FAB'(SLASH)HAPTEN COMPLEXES WITH DIFFERENT METALS IN THE CHELATE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | IGG1-LAMBDA CHA255 FAB (LIGHT CHAIN) | polymer | 215 | 23201.7 | 1 | GenBank (387376) | Mus musculus (house mouse) | |
| 2 | B (H) | IGG1-LAMBDA CHA255 FAB (HEAVY CHAIN) | polymer | 226 | 24011.1 | 1 | PIR (S38864) | Mus musculus (house mouse) | |
| 3 | C (H) | INDIUM (III) ION | non-polymer | 114.8 | 1 | Chemie (IN) | |||
| 4 | D (H) | [(1-[(BIS-CARBOXYMETHYL-AMINO)-METHYL]-2-{4-[3-(2-HYDROXY-ETHYL)-THIOUREIDO]-PHENY}-ETHYL)-CARBOXYMETHYL-AMINO]-ACETIC ACID | non-polymer | 500.5 | 1 | Chemie (EOT) | |||
| 5 | E, F (L, H) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
L: 2 - 215 (GenBank: 387376)
H: 2 - 226 (PIR: S38864)
| PDB | External Database | Details |
|---|---|---|
| Arg 87 | Ile 106 | conflict |
| Leu 97 | His 116 | conflict |
| Ile 140 | Thr 159 | conflict |
| Glu 187 | Ala 206 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Thr 3 | Lys 3 | conflict |
| Val 5 | Leu 5 | conflict |
| Ser 11 | Leu 11 | conflict |
| Phe 27 | Leu 27 | conflict |
| Leu 29 | Phe 29 | conflict |
| Gly 31 | Ser 31 | conflict |
| Glu 32 | Tyr 32 | conflict |
| Thr 33 | Gly 33 | conflict |
| Thr 40 | Ile 40 | conflict |
| Glu 42 | Asp 42 | conflict |
| Thr 51 | Ile 51 | conflict |
| Leu 52 | Ser 52 | conflict |
| Gly 56 | Thr 56 | conflict |
| Phe 57 | Tyr 57 | conflict |
| Phe 59 | Tyr 59 | conflict |
| Ser 61 | Pro 61 | conflict |
| Ala 62 | Asp 62 | conflict |
| Gln 76 | Lys 76 | conflict |
| Asn 78 | Thr 78 | conflict |
| Leu 83 | Met 83 | conflict |
| Asn 84 | Ser 84 | conflict |
| Arg 87 | Lys 87 | conflict |
| Leu 93 | Met 93 | conflict |
| Phe 95 | Tyr 95 | conflict |
| - | Arg 98 | deletion |
| - | Gln 99 | deletion |
| - | Gly 100 | deletion |
| - | Val 101 | deletion |
| - | Thr 103 | deletion |
| - | Met 104 | deletion |
| His 99 | Ile 105 | conflict |
| Val 102 | Ala 108 | conflict |
| His 103 | Tyr 109 | conflict |
| His 106 | Gln 112 | conflict |
| - | Gly 121 | deletion |
| Glu 171 | Gln 178 | conflict |
| Pro 187 | Thr 194 | conflict |
| Arg 188 | Trp 195 | conflict |
| Cys 222 | - | insertion |
| Thr 223 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47212.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 615.3 | |
| All* | Total formula weight | 47828.1 |
