1IJN

Crystal structure of the transthyretin mutant TTR C10A/Y114C

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	TRANSTHYRETIN	polymer	127	13685.3	2	UniProt (P02766) Pfam (PF00576)	Homo sapiens (human)	TBPA, TTR, ATTR
2	C, D, E, F, G... (A, B)	BETA-MERCAPTOETHANOL	non-polymer		78.1	6	Chemie (BME)
3	I, J (A, B)	water	water		18.0	216	Chemie (HOH)

Sequence modifications

A, B: 1 - 127 (UniProt: P02766)

PDB	External Database	Details
Ala 10	Cys 30	engineered mutation
Cys 114	Tyr 134	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	27370.5
Non-Polymers*	Number of molecules	6
	Total formula weight	468.8
All*	Total formula weight	27839.3

*Water molecules are not included.