1IGJ
26-10 FAB:DIGOXIN COMPLEX-AFFINITY AND SPECIFICITY DUE TO SURFACE COMPLEMENTARITY
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | IGG2A-KAPPA 26-10 FAB (LIGHT CHAIN) | polymer | 219 | 24057.7 | 2 | PIR (S52028) | Mus musculus (house mouse) | |
| 2 | B, D (B, D) | IGG2A-KAPPA 26-10 FAB (HEAVY CHAIN) | polymer | 218 | 23307.0 | 2 | PIR (S38950) | Mus musculus (house mouse) | |
| 3 | E, F (B, D) | DIGOXIN | non-polymer | 780.9 | 2 | Chemie (DGX) PubChem (16394506) PubChem (16403371) PubChem (16757666) PubChem (3062) PubChem (16757557) PubChem (45073400) PubChem (45358124) PubChem (22833572) PubChem (24031098) PubChem (24837624) PubChem (52931493) PubChem (53477737) PubChem (44145769) PubChem (58559695) PubChem (58616976) PubChem (44659596) PubChem (45933566) PubChem (44663291) PubChem (70920464) PubChem (70920537) PubChem (71316113) PubChem (2724385) PubChem (57358314) PubChem (58695607) PubChem (58616975) PubChem (59173065) PubChem (60055842) PubChem (60134752) PubChem (66683216) PubChem (176519989) PubChem (30322) PubChem (90346909) PubChem (194123) PubChem (70882148) PubChem (70886579) PubChem (70920463) PubChem (73265414) PubChem (73707466) PubChem (73759829) PubChem (86579129) PubChem (117072395) PubChem (117627601) PubChem (117686431) PubChem (117777085) PubChem (6604360) PubChem (124112976) PubChem (5702042) PubChem (124746530) PubChem (124746526) PubChem (124898317) PubChem (124898843) PubChem (124898845) PubChem (124901334) PubChem (124900891) PubChem (124902043) PubChem (124902038) PubChem (126657056) PubChem (129121359) PubChem (129606042) PubChem (130476760) PubChem (131801316) PubChem (133688115) PubChem (134370198) PubChem (134694175) PubChem (135056324) PubChem (135391146) PubChem (12940990) PubChem (12940955) PubChem (12940972) PubChem (12940977) PubChem (140501613) PubChem (140635266) PubChem (124746527) PubChem (124746528) PubChem (124746529) PubChem (12940973) PubChem (12940984) PubChem (124898321) PubChem (124898324) PubChem (124898326) PubChem (124898844) PubChem (124898847) PubChem (124900892) PubChem (124900895) PubChem (124900897) PubChem (124901335) PubChem (124901336) PubChem (124901337) PubChem (124902041) PubChem (124902044) PubChem (155765066) PubChem (159451917) PubChem (162898443) PubChem (162898448) PubChem (170386604) PubChem (172011968) PubChem (129010261) PubChem (172871753) PubChem (175619468) PubChem (129121360) PubChem (133550128) PubChem (140635282) PubChem (140889045) PubChem (145738015) PubChem (154496482) PubChem (159451916) PubChem (162411201) PubChem (162898444) PubChem (162898445) PubChem (162898446) PubChem (162898447) PubChem (169854558) PubChem (175674824) |
Sequence modifications
A, C: 1 - 214 (PIR: S52028)
B, D: 3 - 227 (PIR: S38950)
| PDB | External Database | Details |
|---|---|---|
| Thr 7 | Ser 7 | conflict |
| Leu 27 | Ile 29 | conflict |
| Asn 34 | Glu 39 | conflict |
| Ala 40 | Pro 45 | conflict |
| Ile 85 | Val 90 | conflict |
| Phe 87 | Tyr 92 | conflict |
| Ser 89 | Phe 94 | conflict |
| Thr 91 | Gly 96 | conflict |
| Thr 92 | Ser 97 | conflict |
| Lys 103 | Asn 108 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Lys 13 | Arg 13 | conflict |
| Arg 19 | Lys 19 | conflict |
| Met 20 | Ile 20 | conflict |
| Ser 24 | Ala 24 | conflict |
| Ile 28 | Thr 28 | conflict |
| Phe 32 | Tyr 32 | conflict |
| Met 34 | Ile 34 | conflict |
| Asn 35 | His 35 | conflict |
| Arg 38 | Lys 38 | conflict |
| Ser 40 | Arg 40 | conflict |
| His 41 | Pro 41 | conflict |
| Lys 43 | Glu 43 | conflict |
| Ser 44 | Gly 44 | conflict |
| Asp 46 | Glu 46 | conflict |
| Tyr 47 | Trp 47 | conflict |
| Tyr 50 | Trp 50 | conflict |
| Ser 52 | Tyr 52 | conflict |
| Tyr 53 | Gly 54 | conflict |
| Val 56 | Asn 57 | conflict |
| Gly 58 | Lys 59 | conflict |
| Gln 61 | Glu 62 | conflict |
| Lys 73 | Thr 74 | conflict |
| Glu 81 | Gln 82 | conflict |
| Arg 82 | Ser 84 | conflict |
| Tyr 91 | Phe 95 | conflict |
| Gly 94 | - | insertion |
| Ser 95 | - | insertion |
| Ser 96 | Arg 98 | conflict |
| Asn 98 | Gly 100 | conflict |
| Trp 100 | Phe 102 | conflict |
| His 105 | Gln 109 | conflict |
| Ala 107 | Thr 111 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 94729.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1561.9 | |
| All* | Total formula weight | 96291.3 |
