1IGJ

26-10 FAB:DIGOXIN COMPLEX-AFFINITY AND SPECIFICITY DUE TO SURFACE COMPLEMENTARITY

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	IGG2A-KAPPA 26-10 FAB (LIGHT CHAIN)	polymer	219	24057.7	2	PIR (S52028)	Mus musculus (house mouse)
2	B, D	IGG2A-KAPPA 26-10 FAB (HEAVY CHAIN)	polymer	218	23307.0	2	PIR (S38950)	Mus musculus (house mouse)
3	B, D	DIGOXIN	non-polymer		780.9	2	Chemie (DGX)

Sequence modifications

A, C: 1 - 214 (PIR: S52028)

PDB	External Database	Details
Thr 7	Ser 7	conflict
Leu 27	Ile 29	conflict
Asn 34	Glu 39	conflict
Ala 40	Pro 45	conflict
Ile 85	Val 90	conflict
Phe 87	Tyr 92	conflict
Ser 89	Phe 94	conflict
Thr 91	Gly 96	conflict
Thr 92	Ser 97	conflict
Lys 103	Asn 108	conflict

B, D: 3 - 227 (PIR: S38950)

PDB	External Database	Details
Lys 13	Arg 13	conflict
Arg 19	Lys 19	conflict
Met 20	Ile 20	conflict
Ser 24	Ala 24	conflict
Ile 28	Thr 28	conflict
Phe 32	Tyr 32	conflict
Met 34	Ile 34	conflict
Asn 35	His 35	conflict
Arg 38	Lys 38	conflict
Ser 40	Arg 40	conflict
His 41	Pro 41	conflict
Lys 43	Glu 43	conflict
Ser 44	Gly 44	conflict
Asp 46	Glu 46	conflict
Tyr 47	Trp 47	conflict
Tyr 50	Trp 50	conflict
Ser 52	Tyr 52	conflict
Tyr 53	Gly 54	conflict
Val 56	Asn 57	conflict
Gly 58	Lys 59	conflict
Gln 61	Glu 62	conflict
Lys 73	Thr 74	conflict
Glu 81	Gln 82	conflict
Arg 82	Ser 84	conflict
Tyr 91	Phe 95	conflict
Gly 94	-	insertion
Ser 95	-	insertion
Ser 96	Arg 98	conflict
Asn 98	Gly 100	conflict
Trp 100	Phe 102	conflict
His 105	Gln 109	conflict
Ala 107	Thr 111	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94729.4
Non-Polymers*	Number of molecules	2
	Total formula weight	1561.9
All*	Total formula weight	96291.3

*Water molecules are not included.