1IA1
Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) and 5-(PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE (GW997)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DIHYDROFOLATE REDUCTASE | polymer | 192 | 22194.5 | 2 | UniProt (P22906) Pfam (PF00186) In PDB | Candida albicans | |
2 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
3 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
4 | A, B | 5-PHENYLSULFANYL-2,4-QUINAZOLINEDIAMINE | non-polymer | 268.3 | 2 | Chemie (TQ3) | |||
5 | water | water | 18.0 | 236 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 44389.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 2217.5 | |
All* | Total formula weight | 46606.5 |