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1IA1

Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) and 5-(PHENYLSULFANYL)-2,4-QUINAZOLINEDIAMINE (GW997)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DIHYDROFOLATE REDUCTASEpolymer19222194.52UniProt (P22906)
Pfam (PF00186)
Candida albicans
2C, F
(A, B)
PHOSPHATE IONnon-polymer95.02Chemie (PO4)
3D, G
(A, B)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.42Chemie (NDP)
4E, H
(A, B)
5-PHENYLSULFANYL-2,4-QUINAZOLINEDIAMINEnon-polymer268.32Chemie (TQ3)
5I, J
(A, B)
waterwater18.0236Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight44389.1
Non-Polymers*Number of molecules6
Total formula weight2217.5
All*Total formula weight46606.5
*Water molecules are not included.

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PDB entries from 2025-12-10

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