1I6V

THERMUS AQUATICUS CORE RNA POLYMERASE-RIFAMPICIN COMPLEX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DNA-DIRECTED RNA POLYMERASE	polymer	314	34846.9	2	UniProt (Q9KWU8) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB	Thermus aquaticus
2	C	DNA-DIRECTED RNA POLYMERASE	polymer	1118	124786.9	1	UniProt (Q9KWU7) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) In PDB	Thermus aquaticus
3	D	DNA-DIRECTED RNA POLYMERASE	polymer	1264	141294.4	1	UniProt (Q9KWU6) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB	Thermus aquaticus
4	E	DNA-DIRECTED RNA POLYMERASE	polymer	99	11642.4	1	UniProt (Q9EVV4) Pfam (PF01192) In PDB	Thermus aquaticus
5	C	RIFAMPICIN	non-polymer		822.9	1	Chemie (RFP)
6	D	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
7	D	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

A, B: 1 - 314 (UniProt: Q9KWU8)

PDB	External Database	Details
Val 112	Gly 112	conflict
Ser 232	Leu 232	conflict

C: 1 - 1119 (UniProt: Q9KWU7)

PDB	External Database	Details
Lys 2	Glu 2	conflict
-	Glu 622	deletion
Val 1111	Ile 1111	conflict

D: 1 - 1524 (UniProt: Q9KWU6)

PDB	External Database	Details
Ala 70	Gly 70	conflict
Ala 77	Gly 77	conflict
Ala 91	Gly 91	conflict
Ala 113	Gly 113	conflict
Ala 139	Gly 139	conflict
Ala 144	Gly 144	conflict
Thr 863	Val 863	conflict
Thr 866	Val 866	conflict
Asn 1009	Lys 1009	conflict

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	347417.5
Non-Polymers*	Number of molecules	3
	Total formula weight	912.7
All*	Total formula weight	348330.2

*Water molecules are not included.