1I6I

CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-AMPPCP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	KINESIN-LIKE PROTEIN KIF1A	polymer	366	41102.2	1	UniProt (P33173) Pfam (PF00225) In PDB	Mus musculus (house mouse)	KIF1A
2	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
3	A	PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER	non-polymer		505.2	1	Chemie (ACP)
4	A	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
5		water	water		18.0	231	Chemie (HOH)

Sequence modifications

A: 1 - 355 (UniProt: P33173)

PDB	External Database	Details
Ala 202	Pro 202	engineered mutation
Asn 356	-	SEE REMARK 999
Thr 357	-	SEE REMARK 999
Val 358	-	SEE REMARK 999
Ser 359	-	SEE REMARK 999
Val 360	-	SEE REMARK 999
Asn 361	-	SEE REMARK 999
His 362	-	SEE REMARK 999
His 363	-	SEE REMARK 999
His 364	-	SEE REMARK 999
His 365	-	SEE REMARK 999
His 366	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41102.2
Non-Polymers*	Number of molecules	3
	Total formula weight	651.7
All*	Total formula weight	41753.8

*Water molecules are not included.