1I5K
STRUCTURE AND BINDING DETERMINANTS OF THE RECOMBINANT KRINGLE-2 DOMAIN OF HUMAN PLASMINOGEN TO AN INTERNAL PEPTIDE FROM A GROUP A STREPTOCOCCAL SURFACE PROTEIN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PLASMINOGEN | polymer | 84 | 9774.9 | 2 | UniProt (P00747) Pfam (PF00051) | Homo sapiens (human) | |
| 2 | C, D (C, D) | M PROTEIN | polymer | 30 | 3635.0 | 2 | UniProt (P49054) Pfam (PF12107) | ||
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 80 (UniProt: P00747)
C, D: 301 - 330 (UniProt: P49054)
| PDB | External Database | Details |
|---|---|---|
| Phe -3 | - | cloning artifact |
| Ser -2 | - | cloning artifact |
| Glu -1 | - | cloning artifact |
| Gly 4 | Cys 188 | engineered mutation |
| Asp 56 | Glu 240 | engineered mutation |
| Tyr 72 | Leu 256 | engineered mutation |
| Ala 79 | Thr 263 | conflict |
| Ala 80 | Thr 264 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Tyr 330 | Arg 114 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 26819.9 | |
| All* | Total formula weight | 26819.9 |
