1I0L
ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-ASPARAGINE MUTANT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE | polymer | 221 | 25523.3 | 2 | UniProt (Q27796) Pfam (PF00156) UniProt (by SIFTS) (Q4DRC4) | Trypanosoma cruzi | |
| 2 | C, F, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 3 | D, H (A, B) | 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE | non-polymer | 136.1 | 2 | Chemie (7HP) | |||
| 4 | E, I (A, B) | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | non-polymer | 390.1 | 2 | Chemie (PRP) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 221 (UniProt: Q27796)
| PDB | External Database | Details |
|---|---|---|
| Lys 23 | Met 23 | SEE REMARK 999 |
| Cys 66 | Ser 66 | SEE REMARK 999 |
| Leu 86 | Val 86 | SEE REMARK 999 |
| Asn 115 | Asp 115 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51046.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1125.3 | |
| All* | Total formula weight | 52172.0 |
