1HX1

CRYSTAL STRUCTURE OF A BAG DOMAIN IN COMPLEX WITH THE HSC70 ATPASE DOMAIN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Heat shock 70 kDa protein 8	polymer	400	44509.1	1	UniProt (P19120) Pfam (PF00012)	Bos taurus (bovine cow domestic cattle domestic cow)	HSC70, Heat shock cognate 71 kDa protein
2	B (B)	BAG family molecular chaperone regulator 1	polymer	114	13157.2	1	UniProt (Q99933) Pfam (PF02179)	Homo sapiens (human)	BAG-1, Bcl-2-associated athanogene 1
3	C (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
4	D, E (A, B)	water	water		18.0	359	Chemie (HOH)

Sequence modifications

A: 4 - 381 (UniProt: P19120)

PDB	External Database	Details
Met -18	-	expression tag
Ser -17	-	expression tag
Tyr -16	-	expression tag
Tyr -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Asp -8	-	expression tag
Tyr -7	-	expression tag
Asp -6	-	expression tag
Pro -5	-	expression tag
Thr -4	-	expression tag
Thr -3	-	expression tag
Glu -2	-	expression tag
Asn -1	-	expression tag
Leu 0	-	expression tag
Tyr 1	-	expression tag
Phe 2	-	expression tag
Gln 3	-	expression tag

B: 151 - 263 (UniProt: Q99933)

PDB	External Database	Details
Gly 150	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57666.3
Non-Polymers*	Number of molecules	1
	Total formula weight	122.1
All*	Total formula weight	57788.4

*Water molecules are not included.