1HVH
NONPEPTIDE CYCLIC CYANOGUANIDINES AS HIV PROTEASE INHIBITORS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 PROTEASE | polymer | 99 | 10757.7 | 2 | UniProt (P04585) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | C (B) | {[4-R(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-1,3-BIS(4-HYDROXYMETHYL)METHYL]-4,7-BIS(PHENYLMETHYL) -2H-1,3-DIAZEPIN-2-YLIDENE]CYANAMIDE} | non-polymer | 590.7 | 1 | Chemie (Q82) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Ala 95 | Cys 151 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21515.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 590.7 | |
| All* | Total formula weight | 22106.0 |
