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1HSG

CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
HIV-1 PROTEASEpolymer9910803.82UniProt (P03367)
Pfam (PF00077)
Human immunodeficiency virus 1
2C
(B)
N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDEnon-polymer613.81Chemie (MK1)
3D, E
(A, B)
waterwater18.0127Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight21607.5
Non-Polymers*Number of molecules1
Total formula weight613.8
All*Total formula weight22221.3
*Water molecules are not included.

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PDB entries from 2025-07-30

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