1HH4
Rac1-RhoGDI complex involved in NADPH oxidase activation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 | polymer | 192 | 21383.9 | 2 | UniProt (P15154) Pfam (PF00071) UniProt (by SIFTS) (P63000) | HOMO SAPIENS (HUMAN) | P21-RAC1, RAS-LIKE PROTEIN TC25 |
| 2 | C, D (D, E) | RHO GDP-DISSOCIATION INHIBITOR 1 | polymer | 204 | 23238.1 | 2 | UniProt (P52565) Pfam (PF02115) | HOMO SAPIENS (HUMAN) | RHO GDI 1, RHO-GDI ALPHA |
| 3 | E, G (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 4 | F, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I, J (D, E) | GERAN-8-YL GERAN | non-polymer | 274.5 | 2 | Chemie (GER) | |||
| 6 | K, L, M, N (A, B, D, E) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 192 (UniProt: P15154)
| PDB | External Database | Details |
|---|---|---|
| Ser 78 | Phe 78 | cloning artifact |
| Pro 1 | Met 1 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 89244.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1484.0 | |
| All* | Total formula weight | 90728.0 |
