1HH4
Rac1-RhoGDI complex involved in NADPH oxidase activation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 | polymer | 192 | 21383.9 | 2 | UniProt (P15154) Pfam (PF00071) UniProt (by SIFTS) (P63000) | HOMO SAPIENS (HUMAN) | P21-RAC1, RAS-LIKE PROTEIN TC25 |
| 2 | C, D (D, E) | RHO GDP-DISSOCIATION INHIBITOR 1 | polymer | 204 | 23238.1 | 2 | UniProt (P52565) Pfam (PF02115) | HOMO SAPIENS (HUMAN) | RHO GDI 1, RHO-GDI ALPHA |
| 3 | E, G (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | F, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | I, J (D, E) | GERAN-8-YL GERAN | non-polymer | 274.5 | 2 | Chemie (GER) | |||
| 6 | K, L, M, N (A, B, D, E) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 192 (UniProt: P15154)
| PDB | External Database | Details |
|---|---|---|
| Ser 78 | Phe 78 | cloning artifact |
| Pro 1 | Met 1 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 89244.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1484.0 | |
| All* | Total formula weight | 90728.0 |
