1H8I
X-ray crystal structure of human alpha-thrombin with a tripeptide phosphonate inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | H | THROMBIN | polymer | 253 | 29208.6 | 1 | UniProt (P00734) Pfam (PF00089) In PDB | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II |
| 2 | I | HIRUDIN I | polymer | 10 | 1363.4 | 1 | UniProt (P01050) In PDB | HIRUDO MEDICINALIS (MEDICINAL LEECH) | LEPIRUDIN |
| 3 | L | THROMBIN | polymer | 27 | 3188.6 | 1 | UniProt (P00734) Pfam (PF09396) In PDB | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II |
| 4 | H | N-[(benzyloxy)carbonyl]-beta-phenyl-D-phenylalanyl-N-[(1S)-4-methoxy-1-phosphonobutyl]-L-prolinamide | non-polymer | 637.7 | 1 | Chemie (PHV) | |||
| 5 | water | water | 18.0 | 365 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 33760.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 637.7 | |
| All* | Total formula weight | 34398.3 |
