1H5U
THE 1.76 A RESOLUTION CRYSTAL STRUCTURE OF GLYCOGEN PHOSPHORYLASE B COMPLEXED WITH GLUCOSE AND CP320626, A POTENTIAL ANTIDIABETIC DRUG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GLYCOGEN PHOSPHORYLASE | polymer | 842 | 97291.2 | 1 | UniProt (P00489) Pfam (PF00343) | ORYCTOLAGUS CUNICULUS (RABBIT) | MYOPHOSPHORYLASE |
| 2 | B (A) | 5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID [1-(4-FLUOROBENZYL)-2-(4-HYDROXYPIPERIDIN-1YL)-2-OXOETHYL]AMIDE | non-polymer | 443.9 | 1 | Chemie (CHI) | |||
| 3 | C (A) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 4 | D (A) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 5 | E (A) | water | water | 18.0 | 355 | Chemie (HOH) |
Sequence modifications
A: 1 - 842 (UniProt: P00489)
| PDB | External Database | Details |
|---|---|---|
| Ile 380 | Leu 380 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 97291.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 871.2 | |
| All* | Total formula weight | 98162.4 |
