1H5S
Thymidylyltransferase complexed with TMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glucose-1-phosphate thymidylyltransferase 1 | polymer | 293 | 32693.5 | 1 | UniProt (P37744) Pfam (PF00483) | Escherichia coli | G1P-TT 1,dTDP-glucose pyrophosphorylase 1,dTDP-glucose synthase 1 |
| 2 | B (B) | Glucose-1-phosphate thymidylyltransferase 1 | polymer | 293 | 32705.4 | 1 | UniProt (P37744) Pfam (PF00483) | Escherichia coli | G1P-TT 1,dTDP-glucose pyrophosphorylase 1,dTDP-glucose synthase 1 |
| 3 | C (C) | Glucose-1-phosphate thymidylyltransferase 1 | polymer | 293 | 32726.5 | 1 | UniProt (P37744) Pfam (PF00483) | Escherichia coli | G1P-TT 1,dTDP-glucose pyrophosphorylase 1,dTDP-glucose synthase 1 |
| 4 | D (D) | Glucose-1-phosphate thymidylyltransferase 1 | polymer | 293 | 32722.5 | 1 | UniProt (P37744) Pfam (PF00483) | Escherichia coli | G1P-TT 1,dTDP-glucose pyrophosphorylase 1,dTDP-glucose synthase 1 |
| 5 | E, F, G, H, I... (A, B, C, D) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 8 | Chemie (TMP) | |||
| 6 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 392 | Chemie (HOH) |
Sequence modifications
A: 1 - 293 (UniProt: P37744)
B: 1 - 293 (UniProt: P37744)
D: 1 - 293 (UniProt: P37744)
| PDB | External Database | Details |
|---|---|---|
| Leu 185 | Gln 185 | conflict |
| Leu 217 | Met 217 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Leu 217 | Met 217 | conflict |
| Gln 288 | Met 288 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Gly 102 | conflict |
| Leu 217 | Met 217 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 130847.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2577.7 | |
| All* | Total formula weight | 133425.4 |
