1H5S

Thymidylyltransferase complexed with TMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Glucose-1-phosphate thymidylyltransferase 1	polymer	293	32693.5	1	UniProt (P37744) Pfam (PF00483) In PDB	Escherichia coli	G1P-TT 1,dTDP-glucose pyrophosphorylase 1,dTDP-glucose synthase 1
2	B	Glucose-1-phosphate thymidylyltransferase 1	polymer	293	32705.4	1	UniProt (P37744) Pfam (PF00483) In PDB	Escherichia coli	G1P-TT 1,dTDP-glucose pyrophosphorylase 1,dTDP-glucose synthase 1
3	C	Glucose-1-phosphate thymidylyltransferase 1	polymer	293	32726.5	1	UniProt (P37744) Pfam (PF00483) In PDB	Escherichia coli	G1P-TT 1,dTDP-glucose pyrophosphorylase 1,dTDP-glucose synthase 1
4	D	Glucose-1-phosphate thymidylyltransferase 1	polymer	293	32722.5	1	UniProt (P37744) Pfam (PF00483) In PDB	Escherichia coli	G1P-TT 1,dTDP-glucose pyrophosphorylase 1,dTDP-glucose synthase 1
5	A, B, C, D	THYMIDINE-5'-PHOSPHATE	non-polymer		322.2	8	Chemie (TMP)
6		water	water		18.0	392	Chemie (HOH)

Sequence modifications

A: 1 - 293 (UniProt: P37744)

PDB	External Database	Details
Leu 185	Gln 185	conflict
Leu 217	Met 217	conflict

B: 1 - 293 (UniProt: P37744)

PDB	External Database	Details
Leu 217	Met 217	conflict
Gln 288	Met 288	conflict

D: 1 - 293 (UniProt: P37744)

PDB	External Database	Details
Ala 102	Gly 102	conflict
Leu 217	Met 217	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	130847.7
Non-Polymers*	Number of molecules	8
	Total formula weight	2577.7
All*	Total formula weight	133425.4

*Water molecules are not included.