1H35

Structures of Human Oxidosqualene Cyclase Inhibitors Bound to an Homologous Enzyme

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	SQUALENE--HOPENE CYCLASE	polymer	631	71650.0	3	UniProt (P33247) Pfam (PF00432) Pfam (PF13243) In PDB	ALICYCLOBACILLUS ACIDOCALDARIUS	SHC
2	A, B, C	(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE	non-polymer		306.4	3	Chemie (C8E)
3	A, B, C	(4'-{[ALLYL(METHYL)AMINO]METHYL}-1,1'-BIPHENYL-4-YL)(4-BROMOPHENYL)METHANONE	non-polymer		420.3	3	Chemie (R01)
4		water	water		18.0	209	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 1 (PDB: 1H35)
A, B, C: 2 - 631 (UniProt: P33247)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	214950.1
Non-Polymers*	Number of molecules	6
	Total formula weight	2180.3
All*	Total formula weight	217130.5

*Water molecules are not included.