1H08

CDK2 in complex with a disubstituted 2, 4-bis anilino pyrimidine CDK4 inhibitor

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
ACELL DIVISION PROTEIN KINASE 2polymer29934002.51
UniProt (P24941)
Pfam (PF00069)
HOMO SAPIENS (HUMAN)@PDBjP33 PROTEIN KINASE
(2R)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OLnon-polymer458.41
(2S)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OLnon-polymer458.41
GLYCEROLnon-polymer92.11
waterwater18.0179

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains1
Total molecular weight34002.5
Non-Polymers*Number of molecules3
Total molecular weight1008.8
All*Total molecular weight35011.3
*Water molecules are not included.