1H08
CDK2 in complex with a disubstituted 2, 4-bis anilino pyrimidine CDK4 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CELL DIVISION PROTEIN KINASE 2 | polymer | 299 | 34002.5 | 1 | UniProt (P24941) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | P33 PROTEIN KINASE |
| 2 | B (A) | (2R)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL | non-polymer | 458.4 | 1 | Chemie (BYP) | |||
| 3 | C (A) | (2S)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL | non-polymer | 458.4 | 1 | Chemie (BWP) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34002.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1008.8 | |
| All* | Total formula weight | 35011.3 |
