1H01
CDK2 in complex with a disubstituted 2, 4-bis anilino pyrimidine CDK4 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CYCLIN-DEPENDENT KINASE 2 | polymer | 298 | 34019.5 | 1 | UniProt (P24941) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | P33 PROTEIN KINASE, CELL DIVISION PROTEIN KINASE 2 |
| 2 | B, C (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | D (A) | (2R)-1-[4-({4-[(2,5-DICHLOROPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL | non-polymer | 448.3 | 1 | Chemie (FAL) | |||
| 4 | E (A) | (2S)-1-[4-({4-[(2,5-DICHLOROPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL | non-polymer | 448.3 | 1 | Chemie (FBL) | |||
| 5 | F (A) | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34019.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1080.9 | |
| All* | Total formula weight | 35100.4 |
