1GZ4
molecular mechanism of the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NAD-DEPENDENT MALIC ENZYME | polymer | 551 | 62552.7 | 4 | UniProt (P23368) Pfam (PF00390) Pfam (PF03949) | HOMO SAPIENS (HUMAN) | HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME, NAD-ME, MALIC ENZYME 2 |
| 2 | E, F, J, K, O... (A, B, C, D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 8 | Chemie (ATP) | |||
| 3 | G, L, Q, V (A, B, C, D) | TARTRONATE | non-polymer | 118.0 | 4 | Chemie (TTN) | |||
| 4 | H, M, R, W (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 5 | I, N, S, X (A, B, C, D) | FUMARIC ACID | non-polymer | 116.1 | 4 | Chemie (FUM) | |||
| 6 | AA, BA, Y, Z (C, D, A, B) | water | water | 18.0 | 572 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 250210.6 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 5213.7 | |
| All* | Total formula weight | 255424.3 |
