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1GRH

INHIBITION OF HUMAN GLUTATHIONE REDUCTASE BY THE NITROSOUREA DRUGS 1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA AND 1-(2-CHLOROETHYL)-3-(2-HYDROXYETHYL)-1-NITROSOUREA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GLUTATHIONE REDUCTASEpolymer47851636.21UniProt (P00390)
Pfam (PF12831)
Pfam (PF00070)
Pfam (PF02852)
HOMO SAPIENS (HUMAN)
2B
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
3C
(A)
FLAVIN-ADENINE DINUCLEOTIDEnon-polymer785.51Chemie (FAD)
4D
(A)
ETHANOLnon-polymer46.11Chemie (EOH)
5E
(A)
waterwater18.0520Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight51636.2
Non-Polymers*Number of molecules3
Total formula weight926.6
All*Total formula weight52562.8
*Water molecules are not included.

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PDB entries from 2026-02-25

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