1GOE
Monitoring the structural Consequences of Phe12-->D-Phe12 and Leu15-->Aib15 substitution in h/r Corticotropin Releasing Hormone: Implications for Design of CRH antagonists.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CORTICOTROPIN RELEASING HORMONE | polymer | 42 | 4734.4 | 1 | UniProt (P06850) Pfam (PF00473) | HOMO SAPIENS |
Sequence modifications
A: 1 - 41 (UniProt: P06850)
| PDB | External Database | Details |
|---|---|---|
| Dpn 12 | Phe 165 | engineered mutation |
| Aib 15 | Leu 168 | engineered mutation |
| Nh2 42 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 4734.4 | |
| All* | Total formula weight | 4734.4 |
