1GM7
Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PENICILLIN G ACYLASE ALPHA SUBUNIT | polymer | 209 | 23854.8 | 1 | UniProt (P06875) In PDB | ESCHERICHIA COLI | NTN, PENICILLIN AMIDOHYDROLASE |
| 2 | B | PENICILLIN G ACYLASE BETA SUBUNIT | polymer | 557 | 62386.5 | 1 | UniProt (P06875) Pfam (PF01804) In PDB | ESCHERICHIA COLI | NTN, PENICILLIN AMIDOHYDROLASE |
| 3 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 20 | Chemie (EDO) | |||
| 4 | B | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | B | PENICILLIN G | non-polymer | 334.4 | 1 | Chemie (PNN) | |||
| 6 | water | water | 18.0 | 930 | Chemie (HOH) |
Sequence modifications
B: 1 - 557 (UniProt: P06875)
| PDB | External Database | Details |
|---|---|---|
| Ala 241 | Asn 530 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86241.3 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 1615.8 | |
| All* | Total formula weight | 87857.1 |
