1GM7
Crystal structures of penicillin acylase enzyme-substrate complexes: Structural insights into the catalytic mechanism
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PENICILLIN G ACYLASE ALPHA SUBUNIT | polymer | 209 | 23854.8 | 1 | UniProt (P06875) | ESCHERICHIA COLI | NTN, PENICILLIN AMIDOHYDROLASE |
| 2 | B (B) | PENICILLIN G ACYLASE BETA SUBUNIT | polymer | 557 | 62386.5 | 1 | UniProt (P06875) | ESCHERICHIA COLI | NTN, PENICILLIN AMIDOHYDROLASE |
| 3 | C, D, E, F, G... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 20 | Chemie (EDO) | |||
| 4 | W (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 5 | X (B) | PENICILLIN G | non-polymer | 334.4 | 1 | Chemie (PNN) PubChem (22298321) PubChem (44314524) PubChem (44318480) PubChem (45791822) PubChem (143725744) PubChem (5904) PubChem (199209) PubChem (2349) PubChem (101718) PubChem (1548925) PubChem (1551461) PubChem (3246457) PubChem (6560153) PubChem (6713834) PubChem (12309625) PubChem (12309626) PubChem (12309627) PubChem (12309628) PubChem (12492121) PubChem (12492123) | |||
| 6 | Y, Z (A, B) | water | water | 18.0 | 930 | Chemie (HOH) |
Sequence modifications
B: 1 - 557 (UniProt: P06875)
| PDB | External Database | Details |
|---|---|---|
| Ala 241 | Asn 530 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86241.3 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 1615.8 | |
| All* | Total formula weight | 87857.1 |
