1GJB
ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | UROKINASE-TYPE PLASMINOGEN ACTIVATOR | polymer | 23 | 2708.2 | 1 | UniProt (P00749) In PDB | Homo sapiens (human) | UPA, U-PLASMINOGEN ACTIVATOR, UROKINASE-PLASMINOGEN ACTIVATOR |
| 2 | B | UROKINASE-TYPE PLASMINOGEN ACTIVATOR | polymer | 253 | 28435.4 | 1 | UniProt (P00749) Pfam (PF00089) In PDB | Homo sapiens (human) | UPA, U-PLASMINOGEN ACTIVATOR, UROKINASE-PLASMINOGEN ACTIVATOR |
| 3 | B | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 4 | B | 2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE | non-polymer | 328.4 | 1 | Chemie (130) | |||
| 5 | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
B: 16 - 250 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Ala 145 | Asn 322 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31143.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 712.6 | |
| All* | Total formula weight | 31856.2 |
