1GI9
A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UROKINASE-TYPE PLASMINOGEN ACTIVATOR | polymer | 23 | 2708.2 | 1 | UniProt (P00749) | Homo sapiens (human) | UPA, U-PLASMINOGEN ACTIVATOR, UROKINASE-PLASMINOGEN ACTIVATOR |
| 2 | B (B) | UROKINASE-TYPE PLASMINOGEN ACTIVATOR | polymer | 245 | 27579.5 | 1 | UniProt (P00749) Pfam (PF00089) | Homo sapiens (human) | UPA, U-PLASMINOGEN ACTIVATOR, UROKINASE-PLASMINOGEN ACTIVATOR |
| 3 | C (B) | 2-(2-HYDROXY-5-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE | non-polymer | 283.3 | 1 | Chemie (123) | |||
| 4 | D, E (B) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
B: 16 - 242 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Ala 145 | Asn 322 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30287.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 667.6 | |
| All* | Total formula weight | 30955.2 |
