1GHW
A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | THROMBIN | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | COAGULATION FACTOR II |
| 2 | B (H) | THROMBIN | polymer | 257 | 29594.1 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | COAGULATION FACTOR II |
| 3 | C (I) | ACETYL HIRUDIN | polymer | 11 | 1491.5 | 1 | UniProt (P28504) | Hirudo medicinalis | |
| 4 | D (H) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | E (H) | 2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE | non-polymer | 253.3 | 1 | Chemie (BMZ) | |||
| 6 | F, G, H (L, H, I) | water | water | 18.0 | 383 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 35182.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 35458.4 |
