1GGI
CRYSTAL STRUCTURE OF AN HIV-1 NEUTRALIZING ANTIBODY 50.1 IN COMPLEX WITH ITS V3 LOOP PEPTIDE ANTIGEN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (L, M) | IGG2A 50.1 FAB (LIGHT CHAIN) | polymer | 218 | 23994.3 | 2 | EMBL (AJ131289) | Mus musculus (house mouse) | |
| 2 | B, E (H, J) | IGG2A 50.1 FAB (HEAVY CHAIN) | polymer | 222 | 23828.8 | 2 | UniProt (P01863) Pfam (PF07654) | ||
| 3 | C, F (P, Q) | HIV-1 V3 LOOP PEPTIDE ANTIGEN | polymer | 16 | 1827.2 | 2 | UniProt (by SIFTS) (P05877) |
Sequence modifications
L, M: 3 - 214 (EMBL: AJ131289)
| PDB | External Database | Details |
|---|---|---|
| Leu 4 | Met 4 | conflict |
| Ser 7 | Thr 7 | conflict |
| Gly 9 | Ala 9 | conflict |
| Ser 27 | Asn 28 | conflict |
| Asp 27 | Arg 31 | conflict |
| Asp 28 | Tyr 32 | conflict |
| Leu 33 | Met 37 | conflict |
| Pro 40 | Ala 44 | conflict |
| Ser 51 | Ala 55 | conflict |
| Ile 55 | Glu 59 | conflict |
| Asp 60 | Ala 64 | conflict |
| Tyr 87 | Phe 91 | conflict |
| Gln 90 | Arg 94 | conflict |
| Asp 94 | Val 98 | conflict |
| Leu 96 | Trp 100 | conflict |
| Ala 100 | Gly 104 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 99300.6 | |
| All* | Total formula weight | 99300.6 |
