1GCQ
CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 | polymer | 61 | 6998.7 | 2 | UniProt (P62993) Pfam (PF00018) | Homo sapiens (human) | |
| 2 | C (C) | VAV PROTO-ONCOGENE | polymer | 70 | 8030.0 | 1 | UniProt (P27870) Pfam (PF00018) | Mus musculus (house mouse) | |
| 3 | D (A) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) | |||
| 4 | E, F, G (A, B, C) | water | water | 18.0 | 189 | Chemie (HOH) |
Sequence modifications
A, B: 159 - 217 (UniProt: P62993)
C: 595 - 660 (UniProt: P27870)
| PDB | External Database | Details |
|---|---|---|
| Gly 157 | - | cloning artifact |
| Ser 158 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 591 | - | cloning artifact |
| Ser 592 | - | cloning artifact |
| His 593 | - | cloning artifact |
| Met 594 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 22027.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 118.2 | |
| All* | Total formula weight | 22145.5 |
