1G6R
A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, C) | ALPHA T CELL RECEPTOR | polymer | 202 | 22298.9 | 2 | UniProt (P01738) Pfam (PF07686) | Mus musculus (house mouse) | |
| 2 | B, G (B, D) | BETA T CELL RECEPTOR | polymer | 237 | 26284.2 | 2 | UniProt (P01852) Pfam (PF07654) | Mus musculus (house mouse) | |
| 3 | C, H (H, I) | MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I MOLECULE | polymer | 274 | 31648.3 | 2 | UniProt (P01901) Pfam (PF00129) Pfam (PF07654) | Mus musculus (house mouse) | |
| 4 | D, I (L, M) | BETA-2 MICROGLOBULIN | polymer | 99 | 11704.4 | 2 | UniProt (P01887) Pfam (PF07654) | Mus musculus (house mouse) | |
| 5 | E, J (P, Q) | SIYR PEPTIDE | polymer | 8 | 1035.2 | 2 |
Sequence modifications
A, C: 1 - 213 (UniProt: P01738)
B, D: 1 - 247 (UniProt: P01852)
| PDB | External Database | Details |
|---|---|---|
| Ala 127 | Gln 142 | conflict |
| Ala 165 | Lys 178 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 97 | Gln 125 | conflict |
| Thr 105 | Arg 127 | conflict |
| Lys 11 | Ala 128 | conflict |
| Tyr 107 | Glu 129 | conflict |
| Phe 108 | Gln 130 | conflict |
| Gly 109 | Phe 131 | conflict |
| Ala 110 | Phe 132 | conflict |
| - | Pro 134 | deletion |
| - | Gly 135 | deletion |
| Ser 115 | Thr 139 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 185941.9 | |
| All* | Total formula weight | 185941.9 |
