1G6R

A FUNCTIONAL HOT SPOT FOR ANTIGEN RECOGNITION IN A SUPERAGONIST TCR/MHC COMPLEX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	ALPHA T CELL RECEPTOR	polymer	202	22298.9	2	UniProt (P01738) Pfam (PF07686) In PDB	Mus musculus (house mouse)
2	B, D	BETA T CELL RECEPTOR	polymer	237	26284.2	2	UniProt (P01852) Pfam (PF07654) In PDB	Mus musculus (house mouse)
3	H, I	MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I MOLECULE	polymer	274	31648.3	2	UniProt (P01901) Pfam (PF00129) Pfam (PF07654) In PDB	Mus musculus (house mouse)
4	L, M	BETA-2 MICROGLOBULIN	polymer	99	11704.4	2	UniProt (P01887) Pfam (PF07654) In PDB	Mus musculus (house mouse)
5	P, Q	SIYR PEPTIDE	polymer	8	1035.2	2

Sequence modifications

A, C: 1 - 213 (UniProt: P01738)

PDB	External Database	Details
Ala 127	Gln 142	CONFLICT
Ala 165	Lys 178	CONFLICT

B, D: 1 - 247 (UniProt: P01852)

PDB	External Database	Details
Gly 97	Gln 125	CONFLICT
Thr 105	Arg 127	CONFLICT
Lys 11	Ala 128	CONFLICT
Tyr 107	Glu 129	CONFLICT
Phe 108	Gln 130	CONFLICT
Gly 109	Phe 131	CONFLICT
Ala 110	Phe 132	CONFLICT
-	Pro 134	DELETION
-	Gly 135	DELETION
Ser 115	Thr 139	CONFLICT

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	185941.9
All*	Total formula weight	185941.9

*Water molecules are not included.