1G55
Structure of human DNMT2, an enigmatic DNA methyltransferase homologue
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA CYTOSINE METHYLTRANSFERASE DNMT2 | polymer | 343 | 39276.4 | 1 | UniProt (O14717) Pfam (PF00145) | Homo sapiens (human) | |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (13792) PubChem (177678424) PubChem (189149) PubChem (439155) PubChem (25210495) PubChem (21125603) PubChem (44361184) PubChem (25203782) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (57544532) PubChem (52224400) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (5284331) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (71170554) PubChem (13231890) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (164157219) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 4 | D (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 6 | F (A) | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence modifications
A: 2 - 391 (UniProt: O14717)
| PDB | External Database | Details |
|---|---|---|
| - | Ser 191 | deletion |
| - | Val 192 | deletion |
| - | His 193 | deletion |
| - | Pro 194 | deletion |
| - | Gln 195 | deletion |
| - | Lys 196 | deletion |
| - | Tyr 197 | deletion |
| - | Ala 198 | deletion |
| - | Met 199 | deletion |
| - | Asp 200 | deletion |
| - | Val 201 | deletion |
| - | Glu 202 | deletion |
| - | Asn 203 | deletion |
| - | Lys 204 | deletion |
| - | Ile 205 | deletion |
| - | Gln 206 | deletion |
| - | Glu 207 | deletion |
| - | Lys 208 | deletion |
| - | Asn 209 | deletion |
| - | Val 210 | deletion |
| - | Glu 211 | deletion |
| - | Pro 212 | deletion |
| - | Asn 213 | deletion |
| - | Ile 214 | deletion |
| - | Ser 215 | deletion |
| - | Phe 216 | deletion |
| - | Asp 217 | deletion |
| - | Gly 218 | deletion |
| - | Ser 219 | deletion |
| - | Ile 220 | deletion |
| - | Gln 221 | deletion |
| - | Cys 222 | deletion |
| - | Ser 223 | deletion |
| - | Gly 224 | deletion |
| - | Lys 225 | deletion |
| - | Asp 226 | deletion |
| - | Ala 227 | deletion |
| - | Ile 228 | deletion |
| - | Leu 229 | deletion |
| - | Phe 230 | deletion |
| - | Lys 231 | deletion |
| - | Leu 232 | deletion |
| - | Glu 233 | deletion |
| - | Thr 234 | deletion |
| - | Ala 235 | deletion |
| - | Glu 236 | deletion |
| - | Glu 237 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39276.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 650.7 | |
| All* | Total formula weight | 39927.1 |
