1G55
Structure of human DNMT2, an enigmatic DNA methyltransferase homologue
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA CYTOSINE METHYLTRANSFERASE DNMT2 | polymer | 343 | 39276.4 | 1 | UniProt (O14717) Pfam (PF00145) | Homo sapiens (human) | |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | D (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | F (A) | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence modifications
A: 2 - 391 (UniProt: O14717)
| PDB | External Database | Details |
|---|---|---|
| - | Ser 191 | deletion |
| - | Val 192 | deletion |
| - | His 193 | deletion |
| - | Pro 194 | deletion |
| - | Gln 195 | deletion |
| - | Lys 196 | deletion |
| - | Tyr 197 | deletion |
| - | Ala 198 | deletion |
| - | Met 199 | deletion |
| - | Asp 200 | deletion |
| - | Val 201 | deletion |
| - | Glu 202 | deletion |
| - | Asn 203 | deletion |
| - | Lys 204 | deletion |
| - | Ile 205 | deletion |
| - | Gln 206 | deletion |
| - | Glu 207 | deletion |
| - | Lys 208 | deletion |
| - | Asn 209 | deletion |
| - | Val 210 | deletion |
| - | Glu 211 | deletion |
| - | Pro 212 | deletion |
| - | Asn 213 | deletion |
| - | Ile 214 | deletion |
| - | Ser 215 | deletion |
| - | Phe 216 | deletion |
| - | Asp 217 | deletion |
| - | Gly 218 | deletion |
| - | Ser 219 | deletion |
| - | Ile 220 | deletion |
| - | Gln 221 | deletion |
| - | Cys 222 | deletion |
| - | Ser 223 | deletion |
| - | Gly 224 | deletion |
| - | Lys 225 | deletion |
| - | Asp 226 | deletion |
| - | Ala 227 | deletion |
| - | Ile 228 | deletion |
| - | Leu 229 | deletion |
| - | Phe 230 | deletion |
| - | Lys 231 | deletion |
| - | Leu 232 | deletion |
| - | Glu 233 | deletion |
| - | Thr 234 | deletion |
| - | Ala 235 | deletion |
| - | Glu 236 | deletion |
| - | Glu 237 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39276.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 650.7 | |
| All* | Total formula weight | 39927.1 |
