1FYT
CRYSTAL STRUCTURE OF A COMPLEX OF A HUMAN ALPHA/BETA-T CELL RECEPTOR, INFLUENZA HA ANTIGEN PEPTIDE, AND MHC CLASS II MOLECULE, HLA-DR1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN | polymer | 181 | 21084.8 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB | Homo sapiens (human) | HLA-DR1, DRA |
| 2 | B | HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR-1 BETA CHAIN | polymer | 192 | 22324.9 | 1 | UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) In PDB | Homo sapiens (human) | HLA-DR1, DRB1 0101 |
| 3 | C | HEMAGGLUTININ HA1 PEPTIDE CHAIN | polymer | 13 | 1506.8 | 1 | UniProt (P03437) In PDB | H3N2 subtype | |
| 4 | D | T-CELL RECEPTOR ALPHA CHAIN | polymer | 212 | 23408.0 | 1 | PIR (RWHUAC) Pfam (PF09291) UniProt (by SIFTS) (P01848) In PDB | Homo sapiens (human) | TCR HA1.7 ALPHA CHAIN |
| 5 | E | T-CELL RECEPTOR BETA CHAIN | polymer | 245 | 27943.3 | 1 | UniProt (P01850) Pfam (PF07654) In PDB | Homo sapiens (human) | TCR HA1.7 BETA CHAIN |
| 6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
E: 3 - 251 (UniProt: P01850)
| PDB | External Database | Details |
|---|---|---|
| Ser 192 | Cys 207 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 96267.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 96710.3 |
