1FYR
DIMER FORMATION THROUGH DOMAIN SWAPPING IN THE CRYSTAL STRUCTURE OF THE GRB2-SH2 AC-PYVNV COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 | polymer | 114 | 13281.0 | 4 | UniProt (P29354) Pfam (PF00017) UniProt (by SIFTS) (P62993) In PDB | Homo sapiens (human) | |
| 2 | I, J, K, L | HEPATOCYTE GROWTH FACTOR RECEPTOR PEPTIDE | polymer | 5 | 599.6 | 4 | UniProt (P08581) In PDB | ||
| 3 | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 50 - 161 (UniProt: P29354)
I, J, K, L: 0 - 3 (UniProt: P08581)
| PDB | External Database | Details |
|---|---|---|
| Gly 48 | - | cloning artifact |
| Ser 49 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Ptr 0 | Tyr 1356 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 55522.4 | |
| All* | Total formula weight | 55522.4 |
