1FTQ
STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GLYCOGEN PHOSPHORYLASE | polymer | 842 | 97291.2 | 1 | UniProt (P00489) Pfam (PF00343) | Oryctolagus cuniculus (rabbit) | |
| 2 | B (A) | (5S,7R,8S,9S,10R)-3-amino-8,9,10-trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dione | non-polymer | 263.2 | 1 | Chemie (GL2) PubChem (46936235) PubChem (445717) PubChem (73353747) PubChem (4632550) PubChem (118719332) | |||
| 3 | C (A) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) PubChem (1051) | |||
| 4 | D (A) | INOSINIC ACID | non-polymer | 348.2 | 1 | Chemie (IMP) PubChem (177678963) PubChem (135464200) PubChem (135533971) PubChem (138454308) PubChem (135398640) PubChem (135402036) PubChem (135449337) PubChem (135486133) PubChem (135530792) PubChem (135567013) PubChem (135705234) PubChem (135854804) PubChem (135889742) PubChem (136026456) PubChem (136073920) PubChem (136217866) PubChem (136259539) PubChem (136716177) PubChem (136766861) PubChem (136811071) PubChem (137162990) PubChem (137168789) PubChem (137257909) PubChem (162510533) PubChem (174152734) | |||
| 5 | E (A) | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 1 - 842 (UniProt: P00489)
| PDB | External Database | Details |
|---|---|---|
| Ile 380 | Leu 380 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 97291.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 858.6 | |
| All* | Total formula weight | 98149.8 |
