1FPG
STRUCTURAL ASPECTS OF THE ALLOSTERIC INHIBITION OF FRUCTOSE-1,6-BISPHOSPHATASE BY AMP: THE BINDING OF BOTH THE SUBSTRATE ANALOGUE 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND CATALYTIC METAL IONS MONITORED BY X-RAY CRYSTALLOGRAPHY
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | FRUCTOSE 1,6-BISPHOSPHATASE | polymer | 335 | 36503.0 | 2 | UniProt (P00636) Pfam (PF00316) Pfam (PF18913) In PDB | Sus scrofa (pig) | |
| 2 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 3 | A, B | 2,5-anhydro-1,6-di-O-phosphono-D-glucitol | non-polymer | 324.1 | 2 | Chemie (AHG) | |||
| 4 | A, B | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 5 | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 335 (UniProt: P00636)
| PDB | External Database | Details |
|---|---|---|
| Gln 20 | Glu 20 | conflict |
| Thr 96 | Ser 96 | conflict |
| Asn 199 | Asp 199 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73006.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1562.4 | |
| All* | Total formula weight | 74568.4 |
