1FKO
CRYSTAL STRUCTURE OF NNRTI RESISTANT K103N MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DMP-266(EFAVIRENZ)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HIV-1 RT, A-CHAIN | polymer | 543 | 62768.7 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | Human immunodeficiency virus 1 | |
| 2 | B (B) | HIV-1 RT, B-CHAIN | polymer | 440 | 51384.0 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | Human immunodeficiency virus 1 | |
| 3 | C (A) | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE | non-polymer | 315.7 | 1 | Chemie (EFZ) |
Sequence modifications
A: 1 - 543 (UniProt: P04585)
B: 1 - 440 (UniProt: P04585)
| PDB | External Database | Details |
|---|---|---|
| Asn 103 | Leu 258 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Asn 103 | Leu 258 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 114152.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 315.7 | |
| All* | Total formula weight | 114468.4 |
