1FDW
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 MUTANT H221Q COMPLEXED WITH ESTRADIOL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 17-BETA-HYDROXYSTEROID DEHYDROGENASE | polymer | 327 | 34963.9 | 1 | UniProt (P14061) Pfam (PF00106) | Homo sapiens (human) | |
| 2 | B (A) | ESTRADIOL | non-polymer | 272.4 | 1 | Chemie (EST) | |||
| 3 | C (A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 1 - 327 (UniProt: P14061)
| PDB | External Database | Details |
|---|---|---|
| Gln 221 | His 221 | engineered mutation |
| Arg 301 | Ala 301 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34963.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 272.4 | |
| All* | Total formula weight | 35236.3 |
