1FDW
HUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 MUTANT H221Q COMPLEXED WITH ESTRADIOL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 17-BETA-HYDROXYSTEROID DEHYDROGENASE | polymer | 327 | 34963.9 | 1 | UniProt (P14061) Pfam (PF00106) | Homo sapiens (human) | |
| 2 | B (A) | ESTRADIOL | non-polymer | 272.4 | 1 | Chemie (EST) PubChem (16757676) PubChem (1807201) PubChem (450) PubChem (177015577) PubChem (5757) PubChem (5998) PubChem (10596) PubChem (14880) PubChem (43912931) PubChem (44284023) PubChem (68570) PubChem (46781508) PubChem (54403267) PubChem (56624791) PubChem (57041922) PubChem (58650893) PubChem (59084698) PubChem (1807200) PubChem (68014581) PubChem (68209947) PubChem (70220248) PubChem (70864205) PubChem (667480) PubChem (667515) PubChem (721867) PubChem (928284) PubChem (1258565) PubChem (5317221) PubChem (91740223) PubChem (5317222) PubChem (5745505) PubChem (6328313) PubChem (6432565) PubChem (6560352) PubChem (6603846) PubChem (101691329) PubChem (6918968) PubChem (6919041) PubChem (7000012) PubChem (7004689) PubChem (7048584) PubChem (7048670) PubChem (118548795) PubChem (7061189) PubChem (7067800) PubChem (9795489) PubChem (9811784) PubChem (9903595) PubChem (9938293) PubChem (12313788) PubChem (11869602) PubChem (11870431) PubChem (12313787) PubChem (12313791) PubChem (12313794) PubChem (162947701) PubChem (166849971) PubChem (126969992) PubChem (129010410) PubChem (129317336) PubChem (130307439) PubChem (130307440) PubChem (143489158) PubChem (144605119) PubChem (145157829) PubChem (145610824) PubChem (154109755) PubChem (172873304) | |||
| 3 | C (A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 1 - 327 (UniProt: P14061)
| PDB | External Database | Details |
|---|---|---|
| Gln 221 | His 221 | engineered mutation |
| Arg 301 | Ala 301 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34963.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 272.4 | |
| All* | Total formula weight | 35236.3 |
