1FCN
Crystal Structure of the E. Coli AMPC Beta-Lactamase Mutant Q120L/Y150E Covalently Acylated with the Substrate Beta-Lactam LORACARBEF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | BETA-LACTAMASE | polymer | 358 | 39538.9 | 2 | UniProt (P00811) Pfam (PF00144) | Escherichia coli | CEPHALOSPORINASE, AMPC BETA-LACTAMASE |
| 2 | C, D (A, B) | LORACABEF (Open form) | non-polymer | 351.8 | 2 | Chemie (LOR) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 358 (UniProt: P00811)
| PDB | External Database | Details |
|---|---|---|
| Leu 117 | Gln 136 | engineered mutation |
| Glu 147 | Tyr 166 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79077.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 703.6 | |
| All* | Total formula weight | 79781.4 |
