1FAV

THE STRUCTURE OF AN HIV-1 SPECIFIC CELL ENTRY INHIBITOR IN COMPLEX WITH THE HIV-1 GP41 TRIMERIC CORE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HIV-1 ENVELOPE PROTEIN CHIMERA	polymer	79	9268.8	1	UniProt (P03069) UniProt (P03377) Pfam (PF07716) In PDB	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
2	C	PROTEIN (TRANSMEMBRANE GLYCOPROTEIN)	polymer	33	4049.3	1	UniProt (P03377) UniProt (by SIFTS) (P04578) In PDB

Sequence modifications

A: 1 - 29 (UniProt: P03069)

PDB	External Database	Details
Ile 2	Leu 253	engineered mutation
Ile 6	Val 257	engineered mutation
Ile 9	Leu 260	engineered mutation
Ile 13	Asn 264	engineered mutation
Ile 16	Leu 267	engineered mutation
Ile 20	Val 271	engineered mutation
Ile 23	Leu 274	engineered mutation
Ile 27	Val 278	engineered mutation

A: 30 - 79 (UniProt: P03377)
C: 125 - 154 (UniProt: P03377)

PDB	External Database	Details
3pa 122	-	conflict
Ggl 123	-	conflict
4ba 124	-	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	13318.1
All*	Total formula weight	13318.1

*Water molecules are not included.