1FAV
THE STRUCTURE OF AN HIV-1 SPECIFIC CELL ENTRY INHIBITOR IN COMPLEX WITH THE HIV-1 GP41 TRIMERIC CORE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HIV-1 ENVELOPE PROTEIN CHIMERA | polymer | 79 | 9268.8 | 1 | UniProt (P03069) UniProt (P03377) Pfam (PF07716) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 2 | B (C) | PROTEIN (TRANSMEMBRANE GLYCOPROTEIN) | polymer | 33 | 4049.3 | 1 | UniProt (P03377) UniProt (by SIFTS) (P04578) |
Sequence modifications
A: 1 - 29 (UniProt: P03069)
A: 30 - 79 (UniProt: P03377)
C: 125 - 154 (UniProt: P03377)
| PDB | External Database | Details |
|---|---|---|
| Ile 2 | Leu 253 | engineered mutation |
| Ile 6 | Val 257 | engineered mutation |
| Ile 9 | Leu 260 | engineered mutation |
| Ile 13 | Asn 264 | engineered mutation |
| Ile 16 | Leu 267 | engineered mutation |
| Ile 20 | Val 271 | engineered mutation |
| Ile 23 | Leu 274 | engineered mutation |
| Ile 27 | Val 278 | engineered mutation |
C: 125 - 154 (UniProt: P03377)
| PDB | External Database | Details |
|---|---|---|
| 3pa 122 | - | conflict |
| Ggl 123 | - | conflict |
| 4ba 124 | - | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 13318.1 | |
| All* | Total formula weight | 13318.1 |
