1F7A
HOW DOES A SYMMETRIC DIMER RECOGNIZE AN ASYMMETRIC SUBSTRATE? A SUBSTRATE COMPLEX OF HIV-1 PROTEASE.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | POL POLYPROTEIN | polymer | 99 | 10800.8 | 2 | UniProt (P03369) Pfam (PF00077) In PDB | Human immunodeficiency virus 1 | |
| 2 | P | CA-P2 SUBSTRATE | polymer | 10 | 1077.3 | 1 | UniProt (by SIFTS) (Q9YX54) In PDB | ||
| 3 | A, B | ACETATE ION | non-polymer | 59.0 | 6 | Chemie (ACT) | |||
| 4 | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P03369)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 63 | engineered mutation |
| Asn 25 | Asp 81 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 22678.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 354.3 | |
| All* | Total formula weight | 23033.1 |
