1F4C
CRYSTAL STRUCTURE OF E. COLI THYMIDYLATE SYNTHASE COVALENTLY MODIFIED AT C146 WITH N-[TOSYL-D-PROLINYL]AMINO-ETHANETHIOL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | THYMIDYLATE SYNTHASE | polymer | 264 | 30559.7 | 2 | UniProt (P0A884) Pfam (PF00303) | Escherichia coli | |
| 2 | C, D, E, G, H (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | F, I (A, B) | N-[TOSYL-D-PROLINYL]AMINO-ETHANETHIOL | non-polymer | 328.4 | 2 | Chemie (TP2) | |||
| 4 | J (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 509 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 264 (UniProt: P0A884)
| PDB | External Database | Details |
|---|---|---|
| Cxm 1 | Met 1 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61119.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1229.3 | |
| All* | Total formula weight | 62348.6 |
